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Signal of the week · Research note · 19 Oct 2026

61 NIH R01 grants dated September 2026 carry $2 million or more each. 52 of them run to 2030 or later

Public award records in Svatantra.ai's signal database show 113 NIH R01 grant records dated September 2026. 61 of them carry $2,000,000 or more obligated on a single award. 52 of the 61 run to 2030 or later. This note sets out the counts, five named records checked against the public award data, NIH's and STAT's fiscal-year figures for context, and what the data does not show: above all, that the feed carries only larger NIH records.

By Jayprakash Mistry, Founder, Svatantra.ai

One email with the PDF attached. You will be on the list for future notes and can unsubscribe from any of them. The list is not sold or shared.

Every number, and where it comes from

The first five figures in the note.

The full table has 16 rows. Each figure is as published on the date shown, with its denominator.

FigureWhat it measuresSource
113NIH R01 grant records dated 1 to 30 September 2026 in the assistance-award feed; 113 distinct award URLs, 69 distinct recipient identifiersSvatantra.ai signal database, count at 16 Oct 2026
61Of the 113, records with $2,000,000 or more obligated as printed; 49 distinct recipient identifiersSvatantra.ai signal database, count at 16 Oct 2026
52Of the 61, records with an end date in 2030 or 2031. 60 of the 61 start in September 2026Svatantra.ai signal database, count at 16 Oct 2026
85%Share of the 61 ending in 2030 or later. Author's arithmetic: 52 / 61 = 85.2%Derived from Svatantra.ai signal database, count at 16 Oct 2026
$2,164,800Median amount of the 113 R01 records; smallest $836,957, largest $5,945,498Svatantra.ai signal database, count at 16 Oct 2026

11 more figures in the PDF, each with its source.

Sources

11 primary releases.

  1. USASpending.gov, REGENTS OF THE UNIVERSITY OF MINNESOTA, award R01AG100759 (Record dated 1 September 2026)
    Total obligation $4,010,962.00. Period of performance 2026-09-01 to 2031-04-30. Date signed 2026-08-24. Awarding agency: National Institutes of Health. Program: Aging Research (93.866). Description begins "ADDRESSING ALZHEIMER'S DISEASE AND ALZHEIMER'S DISEASE RELATED DEMENTIAS NEEDS IN INDIGENOUS POPULATIONS".
    usaspending.gov
  2. USASpending.gov, BOSTON MEDICAL CENTER CORPORATION, award R01DK149649 (Record dated 4 September 2026)
    Total obligation $3,517,102.00. Period of performance 2026-09-04 to 2030-08-31. Date signed 2026-09-03. Awarding agency: National Institutes of Health. Program: Diabetes, Digestive, and Kidney Diseases Extramural Research. Description begins "INDUCED PLURIPOTENT STEM CELL-DERIVED ENDOTHELIAL CELL THERAPY FOR LIVER DISEASE".
    usaspending.gov
  3. USASpending.gov, UNIVERSITY OF MIAMI, award R01DK148692 (Record dated 1 September 2026)
    Total obligation $2,962,847. Period of performance 2026-09-01 to 2030-08-31. Date signed 2026-08-10. Awarding agency: National Institutes of Health. Program: Diabetes, Digestive, and Kidney Diseases Extramural Research. Description begins "LONGITUDINAL DISSECTION OF PANCREATIC" beta-cell "REGENERATION IN HUMAN-BASED IN VIVO MODELS".
    usaspending.gov
  4. USASpending.gov, VANDERBILT UNIVERSITY MEDICAL CENTER, award R01AI197181 (Record dated 1 September 2026)
    Total obligation $3,252,039. Period of performance 2026-09-01 to 2030-08-30. Date signed 2026-08-26. Awarding agency: National Institutes of Health. Program: Allergy and Infectious Diseases Research (93.855). Description begins "TARGETING PATHOGEN RESPIRATION AS AN ANTI-BIOFILM STRATEGY".
    usaspending.gov
  5. USASpending.gov, CHILDREN'S HOSPITAL CORPORATION, THE, award R01HL181224 (Record dated 17 September 2026)
    Total obligation $2,650,223. Period of performance 2026-09-21 to 2031-06-30. Date signed 2026-09-17. Awarding agency: National Institutes of Health. Program: Cardiovascular Diseases Research. Description begins "SHORTENING THE DIAGNOSTIC ODYSSEY FOR CHILDREN WITH RARE PULMONARY DISEASES (RPD)".
    usaspending.gov
  6. STAT, NIH grant funding, fiscal 2026 analysis (Anil Oza, Jonathan Wosen, J. Emory Parker) (2 October 2026)
    About 58,000 projects funded in fiscal 2026, compared with 61,000 in fiscal 2025; the agency spent its "entire external grants budget of roughly $34 billion"; the smaller number of new grants is tied to the "push to fully fund more multiyear grants in advance". STAT notes the 2026 figure may rise because of reporting lags.
    statnews.com
  7. National Institutes of Health, Extramural Nexus, Fiscal Year 2025 By the Numbers: Extramural Grant Investments in Research (12 March 2026)
    "Average size of R01-equivalent awards: $664,005" (up 9.5% from $606,438). Competing R01-equivalent awards 5,471, down 21.8% from 7,000. R01-equivalent success rate 13.0%, down from 18.7%. The decline in awards was "likely due in part to more awards being forward funded than previous years." "We awarded $35.3 billion in competing and noncompeting grants."
    grants.nih.gov
  8. Association of American Medical Colleges, Tracking NIH Awards in FY 2026, data brief (9 September 2026)
    "Entering September, the NIH had obligated $30.2 billion, or 89% of its estimated $34 billion extramural grants budget." "By Aug. 31, the NIH had used multiyear funding to award $1.6 billion to competitive research project grants in FY 2026." "The NIH had funded 1,924 fewer grants than at the same point in FY 2025."
    aamc.org
  9. Congressional Research Service via EveryCRSReport, NIH Grants Policy Under the Second Trump Administration (IF13131) (Updated 17 April 2026)
    NIH says the multiyear policy helps to "increase NIH budget flexibility by no longer encumbering large portions of each year's appropriation". The FY2026 explanatory statement noted "strong concern about the impact of this policy on application success rates". Enacted FY2026 appropriations (P.L. 119-75, Division B, section 240) cap multiyear obligations at the FY2025 level.
    everycrsreport.com
  10. National Institutes of Health, Grants and Funding, Activity codes: R44, RF1, UH3, C06 (Accessed 16 October 2026)
    R44: "Small Business Innovation Research Grants (SBIR) - Phase II", "To help small businesses bring scientific innovations to the marketplace." RF1: "Multi-Year Funded Research Project Grant". UH3: "Exploratory/Developmental Cooperative Agreement Phase II". C06: "Research Facilities Construction Grant".
    grants.nih.gov
  11. Svatantra.ai, Signal database (16 October 2026)
    Counted: signals from one public federal assistance-award feed whose text names the National Institutes of Health as awarding agency, with a record date between 1 and 30 September 2026. 324 records, 324 distinct award URLs, 181 distinct recipient identifiers. Activity code read from the award ID in the URL: 113 R01, of which 61 carry $2,000,000 or more as printed and 52 of those end in 2030 or 2031. Smallest NIH record in the feed, June to October 2026: $836,957. Counts at 16 October 2026.
    svatantra.ai